Type II DM Medication Non-Adherence in Adama Hospital Medical College, Central Ethiopia

Abstract

Background: Type II Diabetes Mellitus is a significant and growing health problem worldwide. In Ethiopia, a limited number of studies have tried to investigate treatment non adherence and associated factors among type II Diabetes Mellitus patients. Therefore, this study was aimed to determine the magnitude of medication non-adherence and its associated factors among type II Diabetes Mellitus patients in Adama hospital medical college, central Ethiopia.    Methods: A facility based cross-sectional study was conducted among 140 Type II Diabetes Mellitus patients in Adama Hospital Medical College, central Ethiopia. We used consecutive sampling method, in which every subject meeting the criteria of inclusion is selected until the required sample size is achieved. A standardized Patient Health Questionnaire (PHQ-9) and Morisky Medication Adherence Scale-8 (MMAS-8) were used to identify the major depressive disorder and medication non adherence, respectively. Data were entered into a computer using EpiData 3.1 then exported to SPSS software version 20 for analysis. Logistic regression analysis was used to identify factors associated with medication non-adherence.    Results: The magnitude of type II Diabetes Mellitus drug non-adherence was 58.6% (95% CI: 54.7, 62.4). Individuals having major depressive disorders (AOR=2.3; 95% CI: 1.1, 5.8), experiencing one or more complications (AOR= 3.3; 95% CI: 1.9, 9.0), and average income greater than 1000 birr (AOR= 0.4; 95% CI: 0.1, 0.9) were found to be independent predictors of medication non-adherence. Conclusion: In this study, the magnitude of medication non-adherence was relatively high among type II Diabetes Mellitus patients. Therefore, health professionals should early screen for diabetes associated complications and comorbid major depressive disorder and treat them early in order to enhance Type II Diabetes Mellitus  patients’ medication adherence.  

Keywords: Medication Non-Adherence; Type II Diabetes Mellitus; Adama; Ethiopia